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100 years 1920 to 2020

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By: F. Lukar, M.A.S., M.D.

Associate Professor, Oklahoma State University Center for Health Sciences College of Osteopathic Medicine

While microbial deposits are common in the rough surface symptoms strep throat generic 50 mg thorazine otc, treatment with antibiotics does not resolve the condition medicine while pregnant thorazine 100mg line. Which of the following conditions may be seen in a patient with an accentuated linea alba A 25-year-old male with multiple jaw osteomas symptoms 8dp5dt purchase thorazine 100 mg visa, epidermoid cysts and multiple supernumerary teeth should undergo which of the following: A treatment of criminals discount thorazine 50mg visa. Leukoedema appears grayish white, typically affecting the buccal mucosa bilaterally. There may be wrinkles or striations present, but these disappear when the mucosa is stretched. Hairy leukoplakia appears as a shaggy white covering of the mucosa, typically on the lateral aspect of the tongue. The first three lesions may appear remarkably similar on inspection, and may only be distinguishable histologically. Epulis fissuratum typically appears at the margin of an ill-fitting denture, and may be grooved by it. It represents the region of friction on the buccal mucosa corresponding to the occlusal line of the teeth. However a markedly accentuated line may be seen in patients who habitually clench or grind their teeth. Intestinal polyps are extremely common in such patients, and colonoscopy is warranted to screen for malignancy since their rate of malignant transformation is so high. Multiple visceral and cutaneous granular cell tumors: ultrastructural and immunocytochemical evidence of Schwann cell origin. A mother brings her 3-month-old infant to your office for evaluation of a rash in the diaper area. On exam there is erythema on the vulva and peri-anal area with sparing of the skin folds. You are called as a consult on an 8-month-old female who has a diaper rash that is unresponsive to treatment with topical antifungals and emollients. On biopsy you see large mononuclear cells with reniform nuclei scattered in the dermis. He sometimes notices blood on his underwear that he attributes to scratching these lesions. This is a description of diaper dermatitis caused by the urine and stool in areas of contact. Psoriasis and peri-anal strep will also cause erythema in this area but does not have the classic sparing of the skin folds. Long-term use of topical super-potent steroids could lead to atrophy and cause skin breakdown but the question stated she used them intermittently. A 55-year-old female with lichen sclerosis of the vagina and perineum has been well-controlled with topical clobetasol propionate ointment intermittently for the last 10 years. She now complains of an area that has increased pain, erythema, occasionally bleeds and does not heal. A 40-year-old man presents with multiple, small, red-brown papules with a flat-to-verrucous surface on the shaft of his penis. A 25-year-old medical student comes to your office because he notes an area of hyperpigmentation on the glans penis. The lesion will start out more erythematous but seems to wax and wane and at times is almost completely resolved. He is otherwise healthy except for seasonal allergies for which he takes an over-the-counter medicine to treat as needed. A 17-year-old female presents to your office with a new pruritic rash involving her axillae, inguinal area, and posterior neck. A lichenoid infiltrate in a band-like distribution which obscures the dermoepidermal junction C. Atypical cells with pale-staining cytoplasm and atypical nuclei, mitoses distributed singly or in clusters in the epithelium 6. This is a typical scenario for a fixed drug reaction related to pseudoephedrine, a common ingredient in cold and allergy medicine. Lichen planus may be on the genitals in both the papular and erosive form but does not wax and wane. It is autosomal dominant and on pathology is described as the "dilapidated brick wall. Shaving is the treatment of choice for trichomycosis axillaris which can affect the pubic hair. Damsted Petersen C, Lundvall L, Kristensen E, Giraldi A: Vulvodynia: definition, diagnosis and treatment. Shah V, Shet T: Scrotal calcinosis results from calcification of cysts derived from hair follicles: a series of 20 cases evaluating the spectrum of changes resulting in scrotal calcinosis.

Scalp medications errors thorazine 50mg online, Face medications while breastfeeding buy genuine thorazine, Parotid Region and Lacrimal Apparatus the Scalp the Face Muscles of the Face Parotid Gland Vessels of the Face and Parotid Region Lymph Nodes of Head and Neck Nerves of the Face 38 medications requiring prior authorization discount thorazine 50mg line. Temporal and Infratemporal Regions Temporal Region Infratemporal Fossa Muscles of Mastication the Temporomandibular Joint 39 symptoms 0f high blood pressure purchase thorazine 100 mg without a prescription. Submandibular Region and Tongue the Submandibular Gland the Sublingual Gland Suprahyoid Muscles the Tongue Muscles of the Tongue Blood Vessels, Lymphatics, and Nerves of the Tongue 40. Cranial Cavity and Vertebral Canal the Cranial Cavity the Meninges Nerves and Arteries in the Cranial Cavity the Spinal Cord 41. Muscles of the Neck, Triangles of the Neck, Deep Cervical Fascia and Lymph Nodes Muscles of the Neck the Platysma the Sternomastoid and Trapezius Infrahyoid Muscles 715 715 716 719 738 741 743 744 745 748 748 751 757 760 765 766 766 768 768 769 772 776 779 779 781 783 784 787 787 795 795 796 803 807 813 813 813 813 813 the Lateral Vertebral Muscles Anterior Vertebral Muscles (Prevertebral Muscles) Deep Muscles of the Back Triangles of the Neck the Posterior Triangle Subdivisions of the Anterior Triangle Suboccipital Triangle Deep Cervical Fascia Investing layer Pretracheal fascia Prevertebral fascia Carotid sheath Lymph Nodes of Head and Neck 42. Blood Vessels of Head and Neck Arteries the Common Carotid Arteries Internal Carotid Artery the External Carotid Arteries the Subclavian Arteries Veins the Internal Jugular Veins the Subclavian Veins the Intracranial Venous Sinuses Tributaries of Internal Jugular Veins in the Neck Other Veins of the Head and Neck 43. Nerves of the Head and Neck Cervical Nerves the Cervical Plexus and its Branches the Cranial Nerves Types of Fibres in Peripheral Nerves Cranial Nerve Nuclei the Olfactory Nerves the Optic Nerve the Oculomotor Nerve the Trochlear Nerve the Abducent Nerve the Trigeminal Nerve the Ophthalmic Nerve the Maxillary Nerve the Facial Nerve the Vestibulocochlear Nerve the Glossopharyngeal Nerve the Vagus Nerve the Accessory Nerve the Hypoglossal Nerve Cervical Part of Sympathetic Trunk 44. Orbit, Eye and Ear the Orbit 814 815 815 821 823 824 826 827 827 828 828 828 829 833 833 833 834 838 847 854 854 855 855 860 861 868 868 870 874 875 879 883 884 887 891 891 893 895 898 908 916 918 923 927 929 931 935 935 Contents of the Orbit Muscles of the Orbit the Lacrimal Gland Nerves and Vessels of Orbit the Eyeball the Ear and Some Related Structures the Auricle External Acoustic Meatus the Middle Ear the Internal Ear 45. Oral Cavity, Nasal Cavity, Pharynx, Larynx, Trachea and Oesophagus the Oral Cavity and Some Related Structures the Oral Cavity the Palate Muscles of the Soft Palate the Teeth the Nasal Cavities and Paranasal Sinuses the Paranasal Sinuses the Pharynx Muscles of the Pharynx the Palatine Tonsils the Larynx Interior of the Larynx Muscles of the Larynx the Trachea the Oesophagus 46. Endocrine Glands of the Head and Neck, Carotid Sinus and Carotid Body the Hypophysis Cerebri the Pineal Body the Thyroid Gland the Parathyroid Glands the Carotid Sinus the Carotid Bodies and Paraganglia 47. Introduction to Central Nervous System and Internal Structure of Spinal Cord Introduction to the Central Nervous System Internal Structure of Spinal Cord 935 935 939 940 943 953 955 956 957 969 976 976 976 978 978 981 984 988 991 994 996 998 1000 1002 1005 1006 1007 1007 1013 1014 1019 1020 1021 1022 1022 1022 1023 1023 1025 1025 1026 1028 1033 1033 1037 49. Gross Anatomy of Brain Gross Anatomy of the Brainstem Preliminary Review of the Internal Structure of the Brainstem Gross Anatomy of the Cerebellum Gross Anatomy of the Cerebral Hemispheres An Introduction to Some Structures Within the Cerebral Hemispheres Important Functional areas of the Cerebral Cortex White Matter of Cerebral Hemispheres 50. Tracts of Spinal Cord and Brainstem; and Cerebellar Connections Tracts of Spinal Cord and Brainstem Descending Tracts Ending in the Spinal Cord Descending Tracts Ending in the Brainstem Ascending Tracts Connections of the Cerebellum Cerebellar Peduncles 51. Diencephalon, Basal Ganglia, Olfactory Region and Limbic System the Diencephalon the Thalamus the Hypothalamus the Metathalamus the Epithalamus the Subthalamic Region the Basal Ganglia the Olfactory Region and Limbic System the Olfactory Region the Olfactory Pathway the Limbic System 53. Pathways for Special Senses Visual Pathway Pathway for Hearing Pathways for Taste Pathways for Smell 55. Ventricles of the Brain and Cerebrospinal Fluid the Lateral Ventricles the Third Ventricle the Fourth Ventricle the Cerebrospinal Fluid 56. Here we will consider some additional features of typical cervical vertebrae, and also some atypical cervical vertebrae. Each transverse process of a typical cervical vertebra is pierced by a foramen transversarium (36. The part of the process in front of the foramen is called the anterior root; and the part behind it is called the posterior root (36. The part lateral to the foramen is usually called the costotransverse bar, but it is more correct to call it the intertubercular bar. The anterior and posterior roots end in thickenings called the anterior and posterior tubercles respectively. One cervical nerve lies in this groove after it passes out of the intervertebral foramen. In the cervical region the costal element forms the anterior root, the costotransverse bar, and both the anterior and posterior tubercles. The laminae of cervical vertebrae are long (transversely) and narrow (vertically). The superior and inferior articular processes form a solid articular pillar that helps to transmit some weight from one vertebra to the next lower one. It looks very different from a typical cervical vertebra as it has no body, and no spine (36. It consists of two lateral masses joined, anteriorly, by a short anterior arch; and, posteriorly, by a much longer posterior arch. A large transverse process, pierced by a foramen transversarium, projects laterally from the lateral mass. The superior aspect of each lateral mass shows an elongated concave facet that articulates with the corresponding condyle of the occipital bone (to form an atlanto-occipital joint). Nodding and lateral movements of the head take place at the two (right and left) atlanto-occipital joints. The medial side of the lateral mass shows a tubercle that gives attachment to the transverse ligament of the atlas (shown in dotted line in 36. This ligament divides the large foramen (bounded by the lateral masses and the arches) into anterior and posterior parts. The anterior part is occupied by the dens (which is an upward projection from the body of the axis). The dens articulates with the posterior aspect of the anterior arch, that bears a circular facet for it. The dens also articulates with the transverse ligament, these two articulations collectively forming the median atlanto-occipital joint. In side-to-side movements of the head the atlas moves with the skull around the pivot formed by the dens. The posterior arch bears a similar projection, the posterior tubercle, which may be regarded as a rudimentary spine. The vertebral artery passes upwards through the foramen transversarium and then runs medially on the groove over the posterior arch.

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Invasion of the carotid can be treated by resection and interposition of a vein graft symptoms job disease skin infections order generic thorazine online. Fixation to the skull base and brachial plexus indicates that the disease is incurable medications zocor purchase 50 mg thorazine with visa, and terminal care support is initiated medications 4 less canada buy thorazine 50 mg lowest price. This occurred after tying the internal jugular vein during a modified radical neck dissection when the other side had been operated on some years previously treatment goals for depression purchase cheap thorazine on-line. The most common primary sites of malignant neck nodes are metastatic squamous carcinoma from the head and neck. Metastatic adenocarcinoma, particularly if the nodes are low in the neck, may be from infraclavicular sites. Excisional rather than incisional biopsies of neck nodes should be performed to avoid implanting malignant disease. Prophylactic neck radiotherapy should be considered to control the potential neck disease. If the primary site is unknown (occult primary), a thorough investigation and continued follow-up will reveal it in 60% of cases. The standard surgical procedure for treating malignant nodal disease in the neck is a modified radical neck dissection. Benign laryngeal tumours Benign laryngeal tumours are encountered only infrequently, the most common being the haemangiomata of childhood and respiratory papillomatosis (p. Benign cartilaginous tumours are also rare and tend to occur in the cricoid cartilage. There is progressive narrowing of the airway, particularly the subglottis, leading to dyspnoea and inspiratory stridor. Conservative surgery is the treatment of choice, as these benign tumours are extremely slow growing. The granular cell myoblastoma, despite its name, arises from Schwann cells rather than muscle cells. The tumour tends to be localized to the true vocal cords, thereby causing dysphonia. Provided the clinician is aware of this pitfall, the tumour can be treated by simple local endoscopic excision. Paragangliomas (chemodectomas; glomus tumours) may occur in the larynx and usually present as painful lesions causing dysphagia. The diagnosis is confirmed histologically, and the majority require conservative surgery. Enlargement will result in additional symptoms due to spread to adjacent regions or metastatic disease. Malignant laryngeal tumours the majority of malignant laryngeal cancers are squamous cell carcinomas. Adenocarcinoma, adenoid cystic carcinoma, sarcoma and lymphoma are extremely rare. This has macroscopic features of malignancy, but microscopically may appear benign. However, malignant features are seen if the histological examination is thorough and detailed. For descriptive purposes, the larynx is divided into three regions: the supraglottis, glottis and subglottis. It is useful to discuss the management of malignant laryngeal disease according to the region primarily affected. The affected area is excised under microscopic control using either microinstruments or a carbon dioxide laser. A very rich decussating lymphatic supply is present, so the frequency of regional nodal metastases is high and may be bilateral. Clinical features Malignancy in the supraglottis presents late owing to the potential space available for expansion. The patient may present with dysphagia, respiratory problems or a metastatic neck node. Endoscopic laryngoscopy allows a full assessment of the extent of the disease, and the precise nature of the disease is confirmed by biopsy. The neck should be painstakingly palpated to detect the presence of any metastatic neck nodes. It usually commences on the free vibrating edge of the true vocal cord and can spread in any direction. Anterior spread to the anterior commissure is a poor prognostic sign as this site is close to cartilage and allows further easy spread to the thyroid gland. Lateral spread into muscle will impair the mobility of the cords and may also reach lymphatic channels. The true cord is devoid of any lymphatic supply and, hence, lesions confined to the cord have an excellent prognosis. Transglottic laryngeal carcinoma Malignant squamous tumours can involve all three regions of the larynx at the time of presentation. Presentation is usually with the onset of respiratory obstruction or the appearance of neck nodes. Radiotherapy is the preferred treatment in patients without regional nodal disease. In the presence of neck disease, laryngectomy with radical neck dissection is the primary form of treatment.

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The openings lie at the lateral angles of a triangular area of the posterior wall of the urinary bladder called the trigone (33 medicine natural purchase thorazine no prescription. Pain starts on the back over lower ribs and shoots downwards and forwards to the inguinal region medicine 0025-7974 order thorazine with american express, scrotum treatment 5th metacarpal fracture 50mg thorazine fast delivery, and sometimes to front of thigh medicine synonym order thorazine 50mg on-line. The clinical correlations of the ureter have been considered in Chapter 30 along with those of the kidneys. However, when distended with urine, part of it extends above the level of the pubic symphysis and comes in contact with the anterior abdominal wall. Urine is formed continuously in the kidneys and is conveyed to the urinary bladder through the ureters. The apex of the bladder gives attachment to the lower end of the median umbilical ligament (33. The superior surface of the bladder is separated by peritoneum from part of the sigmoid colon and from coils of small intestine (33. They are separated from these bones by a mass of fat and by the puboprostatic ligaments (see below). The base of the bladder lies in front of the rectum, but is partly separated from it by the right and left seminal vesicles and the right and left ductus deferens (33. Traced anteriorly this peritoneum becomes continuous with that lining the anterior abdominal wall. In the middle line this peritoneum is raised into a fold called the median umbilical fold because of the presence here of the median umbilical ligament. Traced laterally the peritoneum of the superior surface is reflected on to the lateral pelvic wall. Traced posteriorly the peritoneum on the superior surface of the bladder passes on to the upper part of the base. The peritoneum lined depression between the urinary bladder and the rectum is called the rectovesical pouch (37. In the fetus the rectovesical pouch is much deeper and extends up to the pelvic floor. The lower part of the pouch is obliterated by fusion of the layers of peritoneum lining it. The remains of this peritoneum persist as the rectovesical fascia that separates the lower part of the base of the bladder, and lower down the prostate, from the rectum. Chapter 33 Pelvic Viscera and Peritoneum Relations of Urinary Bladder in the Female 653 1. The greater part of the superior surface of the bladder is lined by peritoneum that separates it from the body of the uterus (33. When traced backwards this peritoneum is reflected on to the front of uterus at the junction of the body with the cervix. The posterior part of the superior surface of the bladder is in direct contact with the upper part of the cervix. The relations of the inferolateral surfaces of the bladder are the same as in the male except that the puboprostatic ligaments are replaced by the pubovesical ligaments. Ligaments of the Urinary Bladder the urinary bladder is kept in place by a number of so-called ligaments. The median umbilical ligament connects the apex of the urinary bladder to the umbilicus. It is the remnant of an embryonic structure the urachus that is derived from the allantoic diverticulum. The fascia over the upper surface of the levator ani (pelvic fascia) is thickened anteriorly to form the medial and lateral puboprostatic ligaments (in the male) or the pubovesical ligaments (in the female). Laterally the same fascia stretches from the bladder to the fascia covering the obturator internus. The lateral margins of the base of the bladder are joined to the lateral pelvic wall by fascia surrounding the veins that pass from the bladder to the internal iliac veins. The median umbilical ligament raises up a median fold of peritoneum called the median umbilical fold (33. In the fetus the right and left umbilical arteries pass from the internal iliac arteries to the umbilicus (on their way to the placenta). Their distal parts become obliterated and form the medial umbilical ligaments that connect the superior vesical arteries to the umbilicus. They raise up folds of peritoneum called the right and left medial umbilical folds. Peritoneum reflected from the superior surface of the bladder to the lateral wall of the pelvis is referred to as the lateral false ligament of the bladder. Two folds of peritoneum (right and left) pass backwards from the lateral margin of the base of the bladder to the sacrum. These folds pass lateral to the rectum and form the lateral boundaries of the rectovesical pouch. These folds are called the sacrogenital folds or the posterior ligaments of the bladder (33. On the posterior wall of the bladder, however, there is a triangular area where the mucosa is relatively fixed. The ureters open into the urinary bladder at the upper lateral corners of the trigone while the upper end of the urethra opens at the lower angle. The upper margin of the trigone forms a ridge stretching between the openings of the two ureters. The urinary bladder is supplied (in the male) by the superior and inferior vesical arteries.

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